The Chevrolet Trail Blazer was northbound on WY 220 near MP 50 in clear weather and dry road conditions while the Freightliner was southbound.
The Chevrolet crossed the center line and entered the southbound lane of travel and collided with the Freightliner. Both vehicles came to rest in the middle of the roadway and became fully engulfed in flames.
The driver of the Chevrolet was pronounced dead at the scene.
He was identified by troopers as 29 year old Damien Coombes.
The driver of the Freightliner was transported via ground ambulance to the Memorial Hospital of Carbon County in Rawlins.